The Molecules of HIV

Note: this site last updated in 2006

Capsid protein

An article from "The Molecules of HIV" (c) Dan Stowell

p24 is the core protein in the HIV virus particle. It forms the "capsid" of the virus, the case in which HIV's RNA genome is kept.

The level of p24 found in the blood serum is an indicator of HIV progression (and similarly, a dropping level of antibodies to p24). Testing for "heat-denatured p24 antigen" was found in a 2002 study to be statistically equivalent to CD4 count and viral load tests.

Testing for protein such as this is 'lower tech' than testing for viral DNA or RNA, and so may hopefully lead to cheaper HIV tests....

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Written by
Dan Stowell

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